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bone mineral density at the distal radius decreased in both actonel and placebo-treated women following 1 year of treatment.
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according to the national osteoporosis foundation, actonel has been shown to reduce the risk of spine and non-spine fractures by 35 to 45 over three years.
There were no significant differences in serum calcium, phosphate, or pth levels between placebo and actonel sodium 5 mg once daily at 3 years.
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