Major surgery if metoprolol is used for a long period of time, it should not be withdrawn before a major surgery; however, the weakened ability of the heart to respond to reflex adrenergic stimulation may increase the risks of surgical procedures and general anesthesia.
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the most common side effects of metoprolol are dizziness, constipation, diarrhea, dry mouth, gas, headache, heartburn, lightheadedness, drowsiness, muscle aches, nausea, and trouble sleeping.
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