Before using this medication, tell your doctor or pharmacist of all prescription and non-prescription herbal products you may use, especially of medicines that thin your blood anticoagulants , such as warfarin rifampicin an antibiotic methotrexate a drug used for suppressing the immune system, and often used in rheumatoid arthritis medicines used to help control high blood pressure and heart failure called ace inhibitors and angiotensin receptor blockers, examples include enalapril, ramipril, losartan and valsartan lithium a medicine used to treat some types of depression diuretics water tablets ciclosporin or tacrolimus drugs used for suppressing the immune system digoxin a medicine for heart failure and irregular heart rhythm minoxidil a drug used to treat high blood pressure salbutamol tablets or oral solution a medicine for asthma birth control pills hormone replacement therapy aspirin, the risk of stomach ulcers is greater if you take etoricoxib with aspirin.
In vitro data in human plasma indicate that doxazosin has no effect on protein binding of digoxin, warfarin, phenytoin, or indomethacin.
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In one major study of patients with heart failure the dig trial , digoxin did not reduce the risk of death, but did reduce the likelihood of being admitted to hospital.
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can increase digoxin levels; monitor levels and signs symptoms of digoxin toxicity.